| 1 |
SCIDE
|
This server was shut down in 2015.
|
1997 |
n.a.
|
n.a.
|
|
|
SCIDE can identify the stabilization center residues in known protein structures.
|
| 2 |
HMMTOP
|
http://www.enzim.hu/hmmtop
|
1999 |
1373511
|
15185696
|
|
|
HMMTOP predicts topology of transmembrane proteins (i.e. number and positions of
transmembrane helices in the amino acid sequences, and the orientation of sequence parts between
helices relative to the membrane). It utilizes an unsupervised learning algorithm for the prediction
and uses amino acid sequence as input.
|
| 3 |
PSORT-B
|
http://www.psort.org/psortb
|
2003 |
n.a.
|
n.a.
|
|
|
PSORT-B is an updated method of PSORT family for prediction of localization in
Gram-negative bacterial proteins.
|
| 4 |
BiSearch
|
http://bisearch.enzim.hu
|
2004 |
1225876
|
4667524
|
|
|
BiSearch is a primer-design algorithm for DNA sequences. It may be used for both
bisulfite converted as well as for original not modified sequences. Users can search various genomes
with the designed primers to avoid non-specific PCR products.
|
| 5 |
SRide
|
http://sride.enzim.hu
|
2005 |
74864
|
n.a.
|
|
|
SRide identifies residues expected to play key roles in the stabilization of proteins.
|
| 6 |
TMDET
|
http://tmdet.enzim.hu
|
2005 |
530643
|
110347
|
|
|
TMDET is an online tool for the detection of the transmembrane regions of membrane
proteins by using their 3D structure only.
|
| 7 |
CMWeb
|
http://cmweb.enzim.hu
|
2012 |
1133541
|
8253
|
|
|
Contact Map WebViewer (or shortly, CMWeb) is an online tool for studying basic
properties of residue-residue contact formation and contact clusters.
|
| 8 |
CCTOP
|
https://cctop.ttk.hu
|
2014 |
2891994
|
4506342
|
|
|
CCTOP predicts the topology i.e. localization of membrane spanning regions and
orientation of segments between them for transmembrane proteins. The prediction is a consensus
of 10 different methods enchanced with available structural and experimental information of any
homologous proteins in the TOPDB database.
|
| 9 |
TmFoldWeb
|
This server was shut down in 2021.
|
2015 |
15843
|
1725
|
|
|
TMFoldWeb is a web server for recognizing the fold of the membrane segments of
transmembrane proteins based on statistical potentials and a topology filtering approach.
|
| 10 |
TSTMP
|
http://tstmp.enzim.ttk.mta.hu
|
2016 |
391515
|
32506
|
|
|
TSTMP is a database designed to help the target selection of human transmembrane
proteins for structural genomics projects.
|
| 11 |
TMCrys
|
http://tmcrys.enzim.ttk.mta.hu
|
2018 |
25558
|
2881
|
|
|
TMCrys predicts the probability of successful solubilization, purification and
crystallization of transmembrane proteins as well as the success for all these three steps together.
|
| 12 |
MemDis
|
https://memdis.ttk.hu
|
2020 |
9510
|
21170
|
|
|
MEMDIS is a novel prediction method, utilizing convolutional neural network and long short-term memory networks for predicting disordered regions in TMPs. MEMDIS achieved the highest prediction accuracy on TMP specific dataset among other popular IDR prediction methods.
|
| 13 |
PolarProtPred
|
https://polarprotpred.ttk.hu
|
2021 |
17733
|
65753
|
|
|
PolarProtPred may offer help to experimentalists to identify or better characterize
molecular networks regulating the distribution of transporters or surface receptors (including viral
entry receptors like COVID-19) by predicting polar distribution of transmembrane proteins.
|
|
Sum |
|
|
7690588 |
24602197 |